General Information

  • ID:  hor002745
  • Uniprot ID:  E9HZ43
  • Protein name:  DENamide4
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  FKGLSHFGEN
  • Length:  10(78-87)
  • Propeptide:  MGLSNFGENGKRFMGLSHFDENGKRFMGLSHFDENGKRFMGLSHFDENGKRFMGLSHFDENGKRFKGLSHFDENGKRFKGLSHFGENGKRFMGLSHFDENGKRFMGLSHFDENGKRFMGLSHFHTKTWT
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9HZ43-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002745_AF2.pdbhor002745_ESM.pdb

Physical Information

Mass: 129595 Formula: C52H74N14O15
Absent amino acids: ACDIMPQRTVWY Common amino acids: FG
pI: 7.55 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 3
Hydrophobicity: -63 Boman Index: -1430
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 39
Instability Index: -3243 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones